SCHEMBL5583650

SCHEMBL5583650

COC(=O)c1ncc(OC(C)=O)c(OC)c1OCc1ccccc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.51
LMNA P02545 2/20 0.48
HPGD P15428 1/20 0.48
PDE4D Q08499 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
NPC1 O15118 1/20 0.43
MAPT P10636 1/20 0.43
HTT P42858 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ALDH1A1 P00352 2/20 0.43
USP2 O75604 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CTSV O60911 1/20 0.42
CTSL P07711 1/20 0.42
KCNA3 P22001 1/20 0.41
BRD4 O60885 1/20 0.40
HTR1A P08908 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583838 0.90 LMNA (0.52) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL5584068 0.83 LMNA (0.59) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL14458095 0.81 PDE4D (0.50) PTPN1LMNAHPGDPDE4DNPC1
SCHEMBL5583586 0.80 PDE4D (0.51) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL27558279 0.79 PTPN1 (0.53) PTPN1LMNAHPGDPDE4DMEN1
SCHEMBL5583599 0.77 LMNA (0.52) PTPN1LMNAHPGDMEN1KMT2A
SCHEMBL5583641 0.76 LMNA (0.53) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL6200588 0.74 PTPN1 (0.64) PTPN1LMNAMEN1KMT2ANPC1
SCHEMBL31636594 0.74 LMNA (0.48) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL5583772 0.73 PTPN1 (0.47) PTPN1LMNAHPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed