SCHEMBL5584068

SCHEMBL5584068

COC(=O)c1ncc(O)c(OC)c1OCc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.59
HPGD P15428 1/20 0.59
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
PDE4D Q08499 1/20 0.42
KCNA3 P22001 1/20 0.41
MEN1 O00255 1/20 0.41
PABPC1 P11940 1/20 0.41
KMT2A Q03164 1/20 0.41
RNASEH1 O60930 1/20 0.41
HTR1A P08908 1/20 0.41
ADRA1D P25100 1/20 0.41
ADRA1A P35348 1/20 0.41
ADRA1B P35368 1/20 0.41
MMP2 P08253 1/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583838 0.87 LMNA (0.52) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL5583650 0.83 PTPN1 (0.51) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL4326071 0.78 LMNA (0.58) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL5583641 0.77 LMNA (0.53) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL2146762 0.77 LMNA (0.50) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL1503281 0.77 LMNA (0.50) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL31636472 0.77 USP2 (0.47) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL5583586 0.76 PDE4D (0.51) LMNAHPGDPDE4DMEN1KMT2A
SCHEMBL25035275 0.76 LMNA (0.55) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL31394853 0.76 LMNA (0.55) LMNAHPGDUSP2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed