SCHEMBL5583838

SCHEMBL5583838

COC(=O)c1ncc(OC)c(OC)c1OCc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
HPGD P15428 1/20 0.52
PDE4D Q08499 1/20 0.49
CTSV O60911 1/20 0.47
CTSL P07711 1/20 0.47
USP2 O75604 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HTR1A P08908 3/20 0.46
ADRA1D P25100 3/20 0.46
ADRA1A P35348 3/20 0.46
ADRA1B P35368 3/20 0.46
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMPD1 P17405 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
HDAC6 Q9UBN7 1/20 0.44
MEN1 O00255 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583650 0.90 PTPN1 (0.51) LMNAHPGDPDE4DCTSVCTSL
SCHEMBL5583586 0.89 PDE4D (0.51) LMNAHPGDPDE4DCTSVCTSL
SCHEMBL14458095 0.88 PDE4D (0.50) LMNAHPGDPDE4DNPC1RAB9A
SCHEMBL5584068 0.87 LMNA (0.59) LMNAHPGDPDE4DCTSVCTSL
SCHEMBL5583641 0.83 LMNA (0.53) LMNAHPGDPDE4DUSP2ALDH1A1
SCHEMBL15746747 0.80 PTPN1 (0.50) LMNAHPGDPDE4DNPC1RAB9A
SCHEMBL2264921 0.78 PTPN1 (0.48) LMNAHPGDPDE4DALDH1A1HTR1A
SCHEMBL5583628 0.77 HPGD (0.60) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL1503281 0.77 LMNA (0.50) LMNAHPGDUSP2ALDH1A1TSHR
SCHEMBL2146762 0.77 LMNA (0.50) LMNAHPGDUSP2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed