SCHEMBL5583641

SCHEMBL5583641

COC(=O)c1nccc(OC)c1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
HPGD P15428 1/20 0.53
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
ALDH1A1 P00352 1/20 0.47
TSHR P16473 1/20 0.47
HSD17B10 Q99714 1/20 0.47
HTR1A P08908 3/20 0.47
ADRA1D P25100 3/20 0.47
ADRA1A P35348 3/20 0.47
ADRA1B P35368 3/20 0.47
BCHE P06276 1/20 0.47
KDM4E B2RXH2 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
SMPD1 P17405 1/20 0.45
HDAC1 Q13547 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583635 0.89 RXRA (0.50) LMNAHPGDMEN1KMT2AHTR1A
SCHEMBL18824977 0.88 HTR1A (0.46) LMNAMEN1KMT2AALDH1A1HTR1A
SCHEMBL14458099 0.88 KCNA3 (0.48) LMNAHPGDMEN1KMT2AHTR1A
SCHEMBL2264912 0.87 SMN1; SMN2 (0.47) LMNAHPGDMEN1KMT2AALDH1A1
SCHEMBL25037143 0.84 LMNA (0.53) LMNAHPGDMEN1KMT2AUSP2
SCHEMBL19463155 0.84 LMNA (0.53) LMNAHPGDMEN1KMT2AUSP2
SCHEMBL31601616 0.84 LMNA (0.53) LMNAHPGDMEN1KMT2AUSP2
SCHEMBL5583838 0.83 LMNA (0.52) LMNAHPGDMEN1KMT2AUSP2
SCHEMBL30439711 0.82 ALDH1A1 (0.50) LMNAMEN1KMT2AALDH1A1TSHR
SCHEMBL5583628 0.81 HPGD (0.60) LMNAHPGDMEN1KMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed