Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723629 | 0.89 | AHR (0.33) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27703067 | 0.86 | MAPT (0.39) | MEN1ALDH1A1MAPTKMT2AGPR84 | |
| SCHEMBL27703068 | 0.85 | CD274 (0.40) | — | |
| SCHEMBL5586519 | 0.79 | NPC1 (0.35) | MEN1MAPTKMT2ASMN1; SMN2ADORA3 | |
| SCHEMBL27723634 | 0.79 | HTR1A (0.38) | ALDH1A1 | |
| SCHEMBL27723752 | 0.75 | HTR7 (0.37) | — | |
| SCHEMBL27723765 | 0.74 | HTR1A (0.33) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL27723655 | 0.74 | PLA2G7 (0.37) | ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5596068 | 0.73 | F2RL3 (0.38) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27723761 | 0.72 | PTGS2 (0.35) | MEN1ALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509174-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | claimed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | claimed |