SCHEMBL5583751

SCHEMBL5583751

COc1ccnc(C(=O)Nc2ccc(OCCCc3ccccc3)cc2)c1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR4 O95977 3/20 0.47
S1PR1 P21453 3/20 0.47
S1PR3 Q99500 3/20 0.47
S1PR5 Q9H228 3/20 0.47
KMT2A Q03164 4/20 0.47
MEN1 O00255 3/20 0.47
MAPT P10636 3/20 0.47
LTA4H P09960 1/20 0.47
NR1H4 Q96RI1 1/20 0.45
NPC1 O15118 5/20 0.45
RAB9A P51151 5/20 0.45
SMN1; SMN2 Q16637 5/20 0.45
TP53 P04637 3/20 0.45
MAPK1 P28482 1/20 0.45
ATM Q13315 1/20 0.45
FFAR1 O14842 1/20 0.44
ALDH1A1 P00352 2/20 0.44
PKM P14618 1/20 0.44
LMNA P02545 1/20 0.44
CYP1A2 P05177 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583750 0.91 SMN1; SMN2 (0.50) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5583857 0.90 RAB9A (0.51) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5583782 0.88 RAB9A (0.57) KMT2AMEN1MAPTLTA4HNPC1
SCHEMBL5583817 0.85 MAPT (0.56) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5586513 0.84 KMT2A (0.47) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL2237038 0.83 RAB9A (0.53) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5583719 0.83 NPC1 (0.53) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5583812 0.82 NPC1 (0.64) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5583568 0.81 MEN1 (0.54) KMT2AMEN1MAPTNPC1RAB9A
SCHEMBL5584055 0.81 ABCC1 (0.53) KMT2AMEN1MAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed