SCHEMBL5583568

SCHEMBL5583568

COc1ccnc(C(=O)Nc2ccc(Nc3ccccc3)cc2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.54
KMT2A Q03164 7/20 0.54
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
RAB9A P51151 5/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.49
MAPK1 P28482 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NPC1 O15118 4/20 0.49
ATR Q13535 2/20 0.48
AURKB Q96GD4 3/20 0.47
AURKA O14965 1/20 0.47
ABCC1 P33527 1/20 0.46
PDGFRA P16234 1/20 0.46
KDR P35968 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
KDM4E B2RXH2 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583719 0.95 NPC1 (0.53) MEN1KMT2ACASP3SENP7RAB9A
SCHEMBL2237038 0.88 RAB9A (0.53) MEN1KMT2ARAB9AMAPTALDH1A1
SCHEMBL5583820 0.88 RAB9A (0.60) MEN1KMT2ARAB9AMAPTALDH1A1
SCHEMBL5583817 0.86 MAPT (0.56) MEN1KMT2ACASP3SENP7RAB9A
SCHEMBL5583857 0.85 RAB9A (0.51) MEN1KMT2ARAB9AMAPTALDH1A1
SCHEMBL5583684 0.85 KDM4E (0.55) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL14284568 0.85 KIF11 (0.52) MAPTMAPK1NPC1AURKBAURKA
SCHEMBL5583750 0.84 SMN1; SMN2 (0.50) MEN1KMT2ARAB9AMAPTALDH1A1
SCHEMBL5584055 0.84 ABCC1 (0.53) MEN1KMT2ARAB9AMAPTNPC1
SCHEMBL5583672 0.84 SCN9A (0.54) MEN1KMT2ARAB9AMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed