Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ATR | Q13535 | 3/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.48 |
| ▸ | TDO2 | P48775 | 2/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | CLK2 | P49760 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.46 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583568 | 0.95 | MEN1 (0.54) | NPC1RAB9AKMT2AMEN1ATR | |
| SCHEMBL2237038 | 0.90 | RAB9A (0.53) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5583820 | 0.90 | RAB9A (0.60) | NPC1RAB9AKMT2AMEN1IDO1 | |
| SCHEMBL5583817 | 0.89 | MAPT (0.56) | NPC1RAB9AKMT2AMEN1ABCC1 | |
| SCHEMBL5583857 | 0.88 | RAB9A (0.51) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5583684 | 0.87 | KDM4E (0.55) | NPC1RAB9AKMT2AMEN1TDO2 | |
| SCHEMBL5583770 | 0.87 | GRM4 (0.52) | NPC1RAB9AKMT2AMEN1CASP3 | |
| SCHEMBL5583750 | 0.87 | SMN1; SMN2 (0.50) | NPC1RAB9AKMT2AMEN1ALDH1A1 | |
| SCHEMBL5584055 | 0.87 | ABCC1 (0.53) | NPC1RAB9AKMT2AMEN1ATR | |
| SCHEMBL5583672 | 0.86 | SCN9A (0.54) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |