Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.46 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PLAU | P00749 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726679 | 0.80 | ELANE (0.60) | ELANEPOLBF2PLAUNPC1 | |
| SCHEMBL9987666 | 0.79 | ELANE (0.55) | ELANEF2PLAU | |
| SCHEMBL28076707 | 0.79 | PDGFRA (0.62) | ELANEPOLBPDGFRACDK5TYRO3 | |
| SCHEMBL27971365 | 0.79 | ELANE (0.54) | ELANEPOLBPDGFRACDK5TYRO3 | |
| SCHEMBL8304178 | 0.78 | ELANE (0.54) | ELANEPOLBPDGFRACDK5TYRO3 | |
| SCHEMBL2674135 | 0.78 | MAP2K4 (0.44) | ELANEF2PLAUNPC1RAB9A | |
| SCHEMBL6113809 | 0.76 | ELANE (0.69) | ELANEPOLBF2PLAU | |
| SCHEMBL11903978 | 0.74 | RORC (0.61) | ELANERORC | |
| SCHEMBL2432444 | 0.73 | ELANE (0.74) | ELANEF2PLAU | |
| SCHEMBL127188 | 0.71 | ELANE (0.43) | ELANEPOLBPDGFRACDK5TYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841405-A1 | COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION COMPRISING AN EUGLENA EXTRACT | Sederma (FR) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006075311-A1 | COSMETIC OR DERMOPHARMACEUTICAL COMPOSITION COMPRISING AN EUGLENA EXTRACT | SEDERMA (FR) | 2006-07-20 | — | — | WO | disclosed |