Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2263268 | 0.96 | LTA4H (0.44) | LTA4HTSHRRIPK1ALDH1A1MAPK1 | |
| SCHEMBL2263392 | 0.92 | MAOB (0.41) | LTA4HTSHRALDH1A1GAAKMT2A | |
| SCHEMBL1895338 | 0.86 | LTA4H (0.42) | LTA4HTSHRSLC6A4RIPK1SLC6A2 | |
| SCHEMBL2268413 | 0.85 | TEAD4 (0.41) | TSHRSLC6A4ALDH1A1HTTLMNA | |
| SCHEMBL2265983 | 0.83 | POLB (0.42) | LTA4HTSHRSLC6A4SLC6A2ALDH1A1 | |
| SCHEMBL2263266 | 0.83 | MAOB (0.46) | SLC6A2MAPK1L3MBTL1LMNAGAA | |
| SCHEMBL2269357 | 0.82 | SMN1; SMN2 (0.47) | TSHRSLC6A4SLC6A2ALDH1A1LMNA | |
| SCHEMBL1451604 | 0.82 | LTA4H (0.46) | LTA4HTSHRSLC6A4RIPK1SLC6A2 | |
| SCHEMBL2264473 | 0.81 | CYP1A2 (0.38) | SLC6A4SLC6A2ALDH1A1MAPK1HTT | |
| SCHEMBL2264018 | 0.81 | KDM4E (0.44) | TSHRALDH1A1MAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | claimed |
| US-20060235192-A1 | Soluble, low dielectrical constant, unsymmetrical polyimide and a method for preparing the same | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) | 2006-10-19 | — | — | US | claimed |
| CN-1273517-C | Soluble asymmetric polyimide and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY (CN) | 2006-09-06 | — | — | CN | claimed |
| CN-1687188-A | Soluble asymmetric polyimide and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY (CN) | 2005-10-26 | — | — | CN | claimed |
| CN-1213658-C | Pyridinecarboxamide derivative and pest control agent containing same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2005-08-10 | — | — | CN | claimed |
| CN-1329596-A | Pyridinecarboxamide derivative and pest control agent containing same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2002-01-02 | — | — | CN | claimed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | claimed |
| CN-102432552-A | Quinazoline analogs as receptor tyrosine kinase inhibitors | ARRAY BIOPHARMA INC | 2012-05-02 | — | — | CN | disclosed |
| CN-100365039-C | Polymerizable composition, thermoplastic resin composition, crosslinked resin, and crosslinked resin composite materials | ZEON CORP (JP) | 2008-01-30 | — | — | CN | disclosed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| US-20060235192-A1 | Soluble, low dielectrical constant, unsymmetrical polyimide and a method for preparing the same | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) | 2006-10-19 | — | — | US | disclosed |
| CN-1273517-C | Soluble asymmetric polyimide and preparation method thereof | CHANGCHUN APPLIED CHEMISTRY (CN) | 2006-09-06 | — | — | CN | disclosed |
| US-20060122064-A1 | Amides and method for plant diseases control with the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-06-08 | — | — | US | disclosed |
| EP-1577290-A1 | AMIDE COMPOUND AND METHOD OF CONTROLLING PLANT DISEASE WITH THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-09-21 | — | — | EP | disclosed |
| CN-1213658-C | Pyridinecarboxamide derivative and pest control agent containing same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2005-08-10 | — | — | CN | disclosed |
| CN-1329596-A | Pyridinecarboxamide derivative and pest control agent containing same as active ingredient | MEIJI SEIKA KAISHA (JP) | 2002-01-02 | — | — | CN | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |
| CN-1187814-A | (hetero) aryloxy-, -thio-and-aminocrotonates, preparation and use thereof | BASF AG (DE) | 1998-07-15 | — | — | CN | disclosed |
| CN-1161687-A | Phenylacetic acid alkyl esters | BASF AG (DE) | 1997-10-08 | — | — | CN | disclosed |
| US-4277557-A | PROPYNE ANTIFOGGING AGENT | AGFA-GEVAERT, A.G. (DE) | 1981-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122064-A1 | Amides and method for plant diseases control with the same | ARG1, ARGLU1, ARG2 | LTA4H 1358/4885TSHR 851/4885SLC6A4 4330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.