SCHEMBL5583834

SCHEMBL5583834

CC(C)(C)c1ccc(Oc2cc[c]cc2)c(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
HPGD P15428 3/20 0.37
RAB9A P51151 2/20 0.37
MAPT P10636 2/20 0.37
MAPK1 P28482 2/20 0.37
NPC1 O15118 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
APEX1 P27695 1/20 0.34
NPSR1 Q6W5P4 2/20 0.34
FGFR2 P21802 2/20 0.34
KDM4E B2RXH2 1/20 0.33
ICAM1 P05362 1/20 0.33
SELE P16581 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2262676 0.85 KDM4E (0.44) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL14586631 0.81 TSHR (0.47) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL5583639 0.80 ALDH1A1 (0.62) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL30689270 0.78 MAPT (0.42) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL8569226 0.77 EZH2 (0.40) ALDH1A1MAPTMAPK1KDM4EL3MBTL1
SCHEMBL8567630 0.77 SLC6A4 (0.39) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL2261897 0.77 NCOA1 (0.39) ALDH1A1RAB9AMAPTNPC1NPSR1
SCHEMBL24213309 0.77 CA2 (0.50) ALDH1A1HPGDMAPTMAPK1CA1
SCHEMBL1282313 0.76 MAPT (0.61) ALDH1A1HPGDRAB9AMAPTMAPK1
SCHEMBL4856988 0.74 ALDH1A1 (0.41) ALDH1A1HPGDRAB9AMAPTAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US claimed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP claimed
EP-3810720-A1 EXTRUDED PET FILMS WITH PHOTOSTABLE DYES FOR COLOR CONVERSION BASF SE (DE) 2021-04-28 EP disclosed
CN-112292436-A Extruded PET film with light stable dyes for color conversion 巴斯夫欧洲公司 2021-01-29 CN disclosed
WO-2019243288-A1 EXTRUDED PET FILMS WITH PHOTOSTABLE DYES FOR COLOR CONVERSION BASF SE (DE) 2019-12-26 WO disclosed
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed