Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL278540 | 0.84 | RIPK1 (0.53) | EZH2FFAR1RIPK1ALDH1A1MAPK1 | |
| SCHEMBL919536 | 0.81 | LTA4H (0.48) | FFAR1ALDH1A1MAPK1HTTL3MBTL1 | |
| SCHEMBL127278 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTTDP1ATMCYP1A2 | |
| SCHEMBL30500977 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HTTTDP1ATMCYP1A2 | |
| SCHEMBL15864087 | 0.79 | CA2 (0.39) | ALDH1A1TDP1TSHRKDM4E | |
| SCHEMBL12412410 | 0.79 | ALDH1A1 (0.55) | EZH2FFAR1RIPK1ALDH1A1MAPK1 | |
| SCHEMBL12862911 | 0.79 | L3MBTL1 (0.45) | EZH2FFAR1RIPK1ALDH1A1MAPK1 | |
| SCHEMBL27488193 | 0.79 | RIPK1 (0.41) | EZH2FFAR1RIPK1ALDH1A1MAPK1 | |
| SCHEMBL28367828 | 0.78 | ALDH1A1 (0.53) | EZH2FFAR1RIPK1ALDH1A1MAPK1 | |
| SCHEMBL2091646 | 0.78 | L3MBTL1 (0.44) | RIPK1ALDH1A1MAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5814646-A | TREATING THE PROGRESSION OF ALZHEIMER'S DISEASE, BRAIN DISORDERS | ELI LILLY AND COMPANY (US) | 1998-09-29 | — | — | US | disclosed |