Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5583878 | 0.91 | MAPK14 (0.52) | KMT2AHPGDTP53GLAPOLB | |
| SCHEMBL6372807 | 0.87 | KMT2A (0.51) | KMT2APOLBNPSR1MAPTL3MBTL1 | |
| SCHEMBL5583623 | 0.85 | RAB9A (0.50) | KMT2AHPGDTP53POLBKDM4E | |
| SCHEMBL5583644 | 0.84 | RAB9A (0.52) | KMT2AHPGDTP53POLBMEN1 | |
| SCHEMBL5515965 | 0.82 | KMT2A (0.61) | KMT2AGSK3BALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL19937647 | 0.81 | KMT2A (0.43) | KMT2AHPGDTP53GLAKDM4E | |
| SCHEMBL2486939 | 0.80 | EPHX2 (0.53) | KMT2AHPGDMAPTMEN1ALDH1A1 | |
| SCHEMBL14284398 | 0.80 | EGLN1 (0.46) | KMT2AHTT | |
| SCHEMBL5583817 | 0.80 | MAPT (0.56) | KMT2ATP53POLBKDM4ENPSR1 | |
| SCHEMBL5583719 | 0.80 | NPC1 (0.53) | KMT2AHPGDKDM4EMAPTGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE39991-E1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2008-01-01 | — | — | US | disclosed |
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |