SCHEMBL5583644

SCHEMBL5583644

COc1ccnc(C(=O)NCCCCc2ccccc2)c1O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.52
TP53 P04637 1/20 0.49
HPGD P15428 2/20 0.49
TAAR1 Q96RJ0 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
KMT2A Q03164 3/20 0.48
MEN1 O00255 1/20 0.48
POLB P06746 1/20 0.48
ALDH1A1 P00352 1/20 0.48
GFER P55789 1/20 0.48
ASPH Q12797 1/20 0.47
KDM8 Q8N371 1/20 0.47
DRD2 P14416 1/20 0.46
DRD3 P35462 1/20 0.46
MLYCD O95822 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583623 0.96 RAB9A (0.50) RAB9ATP53HPGDTAAR1SMN1; SMN2
SCHEMBL14284400 0.85 PTAFR (0.56) SMN1; SMN2
SCHEMBL5583853 0.84 KMT2A (0.58) TP53HPGDSMN1; SMN2KMT2AMEN1
SCHEMBL14284530 0.84 ALOX5 (0.43) RAB9AKMT2AMEN1
SCHEMBL5583874 0.83 NAAA (0.50)
SCHEMBL5583619 0.83 NAAA (0.50)
SCHEMBL5583825 0.83 NAAA (0.50)
SCHEMBL2486939 0.80 EPHX2 (0.53) HPGDSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL5583751 0.79 S1PR4 (0.47) RAB9ATP53SMN1; SMN2KMT2AMEN1
SCHEMBL14284528 0.79 ATM (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed