SCHEMBL5583623

SCHEMBL5583623

COc1ccnc(C(=O)NCCCc2ccccc2)c1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.50
NPC1 O15118 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
TSHR P16473 2/20 0.49
HPGD P15428 2/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 1/20 0.49
HTT P42858 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
HSD17B10 Q99714 1/20 0.49
NLRP1 Q9C000 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
EPHX2 P34913 1/20 0.48
TP53 P04637 1/20 0.48
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
USP2 O75604 1/20 0.47
POLB P06746 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583644 0.96 RAB9A (0.52) RAB9ATAAR1HPGDALDH1A1SMN1; SMN2
SCHEMBL14284400 0.89 PTAFR (0.56) SMN1; SMN2EPHX2
SCHEMBL5583853 0.85 KMT2A (0.58) HPGDMAPTALDH1A1HTTNPSR1
SCHEMBL14284530 0.83 ALOX5 (0.43) RAB9AMEN1KMT2A
SCHEMBL5583825 0.81 NAAA (0.50) HTTKDM4E
SCHEMBL5583619 0.81 NAAA (0.50) HTTKDM4E
SCHEMBL5583874 0.81 NAAA (0.50) HTTKDM4E
SCHEMBL2486939 0.81 EPHX2 (0.53) HPGDMAPTALDH1A1HTTSMN1; SMN2
SCHEMBL5583751 0.80 S1PR4 (0.47) RAB9ANPC1MAPTALDH1A1SMN1; SMN2
SCHEMBL14307432 0.80 ALDH1A1 (0.41) RAB9ANPC1HPGDMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed