Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7135820 | 0.89 | ALDH1A1 (0.60) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL38655942 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL5583988 | 0.88 | ALDH1A1 (0.65) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL8393234 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL5186181 | 0.80 | ALDH1A1 (0.74) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL3202573 | 0.79 | ALDH1A1 (0.72) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL17339105 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL291299 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL8957406 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTNPC1 | |
| SCHEMBL874591 | 0.79 | ALDH1A1 (0.56) | ALDH1A1TSHRHPGDHTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425417-B1 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECH GMBH (DE) | 2007-10-31 | — | — | EP | disclosed |
| US-20050147984-A1 | Interaction detection on several probe arrays | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| EP-1425417-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | Clondiag Chip Technologies GmbH (DE) | 2004-06-09 | — | — | EP | disclosed |
| US-20030181742-A1 | Process for the preparation of pregnane derivatives | KURARAY CO., LTD. (JP) | 2003-09-25 | — | — | US | disclosed |
| EP-1325928-A1 | PROCESS FOR THE PREPARATION OF PREGNANE DERIVATIVES | Kuraray Co., Ltd. (JP) | 2003-07-09 | — | — | EP | disclosed |
| WO-2003018838-A2 | INTERACTION DETECTION ON SEVERAL PROBE ARRAYS | CLONDIAG CHIP TECHNOLOGIES GMBH (DE) | 2003-03-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181742-A1 | Process for the preparation of pregnane derivatives | CYP21A2, CYP11B2, CYP17A1 | ALDH1A1 1934/4885TSHR 1634/4885HPGD 190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.