SCHEMBL5584054

SCHEMBL5584054

CC(C)(C)c1ccc(Oc2ccc(NC(=O)c3ncccc3O)cc2)c(C(C)(C)C)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSF1R P07333 1/20 0.51
RET P07949 1/20 0.51
PDGFRB P09619 1/20 0.51
KIT P10721 1/20 0.51
PDGFRA P16234 1/20 0.51
FLT3 P36888 1/20 0.51
P2RY1 P47900 3/20 0.47
P2RY14 Q15391 2/20 0.47
GRM4 Q14833 3/20 0.45
RAB9A P51151 2/20 0.44
NPC1 O15118 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
LMNA P02545 1/20 0.44
RAF1 P04049 1/20 0.43
TLR7 Q9NYK1 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
TRPV1 Q8NER1 4/20 0.41
NR1I2 O75469 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5583813 0.87 CSF1R (0.55) CSF1RRETPDGFRBKITPDGFRA
SCHEMBL5583759 0.84 KDR (0.47) PDGFRARAB9ASMN1; SMN2LMNAMAPT
SCHEMBL14284358 0.78 TLR7 (0.62) RAB9ANPC1TLR7MAPTTRPV1
SCHEMBL5583780 0.76 PNLIP (0.63) RAB9ANPC1SMN1; SMN2LMNAMAPT
SCHEMBL5583621 0.74 TLR7 (0.57) RETP2RY1TLR7
SCHEMBL7078360 0.73 MAPT (0.44) RAF1MAPTMAPK1NPSR1
SCHEMBL5583850 0.71 KDR (0.50) PDGFRARAB9ASMN1; SMN2LMNARAF1
SCHEMBL18027788 0.71 KDM4E (0.73) CSF1RRETPDGFRBKITPDGFRA
Phosphoric Acid SCHEMBL27975098 0.70 MEN1 (0.46) LMNAMAPTNPSR1
SCHEMBL14284357 0.69 MAPT (0.64) CSF1RRETPDGFRBKITPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed