SCHEMBL7078360

SCHEMBL7078360

CC(C)(C)c1ccc(Oc2ccc(NC(=O)c3cccc(NC=O)c3O)cc2)c(C(C)(C)C)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.44
MAPK1 P28482 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
NR1H4 Q96RI1 4/20 0.43
PLG P00747 2/20 0.42
KLK1 P06870 2/20 0.42
KLK6 Q92876 2/20 0.42
KLKB1 P03952 1/20 0.42
RXFP1 Q9HBX9 2/20 0.42
PPARG P37231 1/20 0.41
PPARA Q07869 1/20 0.41
TP53 P04637 1/20 0.41
KDR P35968 1/20 0.41
PARG Q86W56 1/20 0.40
PKM P14618 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
GAA P10253 2/20 0.39
RAF1 P04049 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073943 0.88 PKM (0.47) MAPK1NR1H4PLGKLK1KLK6
SCHEMBL7074417 0.85 TLR8 (0.49) MAPK1PLGKLK1KLK6KLKB1
SCHEMBL7080494 0.78 PNLIP (0.62) MAPTMAPK1TP53MEN1KMT2A
SCHEMBL7074399 0.78 PNLIP (0.61) MAPK1RXFP1MEN1KMT2APOLB
SCHEMBL7077257 0.77 RXFP1 (0.60) RXFP1KDRRAF1
SCHEMBL7074805 0.77 PNLIP (0.67) PARGMEN1KMT2AHTT
SCHEMBL5584054 0.73 CSF1R (0.51) MAPTMAPK1NPSR1RAF1
SCHEMBL7077402 0.72 PNLIP (0.43) MAPTMAPK1KLK1TP53MEN1
SCHEMBL1457071 0.72 RXFP1 (0.56) RXFP1TP53MEN1KMT2AALDH1A1
SCHEMBL7078518 0.72 PNLIP (0.41) MAPTMAPK1KLKB1RXFP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP claimed
EP-0848700-B1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2003-07-02 EP disclosed
US-6548549-B1 Fungicides, insecticides, bactericides; applying to plant BAYER AKTIENGESELLSCHAFT (DE) 2003-04-15 US disclosed
US-6001879-A SUITABLE FOR CONTROLLING PESTS, PREFERABLY FUNGI, INSECTS AND BACTERIA, IN PLANTS AND INDUSTRIAL MATERIALS; METHODS OF THEIR SYBNTHESIS INCLUDING REACTING AMINOSALICYLAMIDES WITH ACYLATING AGENTS BAYER AKTIENGESELLSCHAFT (DE) 1999-12-14 US disclosed
EP-0848700-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AG (DE) 1998-06-24 EP disclosed
WO-1997008135-A1 ACYLAMINOSALICYLIC ACID AMIDES AND THEIR USES AS PESTICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-03-06 WO disclosed