Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.55 |
| ▸ | RET | P07949 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | KIT | P10721 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | FLT3 | P36888 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14284358 | 0.88 | TLR7 (0.62) | TRPV1RAB9ANPC1TLR7 | |
| SCHEMBL5584054 | 0.87 | CSF1R (0.51) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL5583780 | 0.86 | PNLIP (0.63) | RAB9AMAPK1NPC1ATMSMN1; SMN2 | |
| SCHEMBL5583621 | 0.81 | TLR7 (0.57) | RETTLR7 | |
| SCHEMBL5583850 | 0.80 | KDR (0.50) | PDGFRATRPV1RAB9APKMSMN1; SMN2 | |
| SCHEMBL14514567 | 0.80 | PNLIP (0.74) | RAB9APKMNPC1SMN1; SMN2LMNA | |
| SCHEMBL18027788 | 0.77 | KDM4E (0.73) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL7302329 | 0.76 | RAB9A (0.76) | NAMPTRAB9AGALR3MAPK1NPC1 | |
| SCHEMBL13201028 | 0.75 | ATR (0.61) | CSF1RRETPDGFRBKITPDGFRA | |
| SCHEMBL30994893 | 0.75 | PGR (0.74) | TRPV1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7183278-B1 | Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component | MEIJI SEIKA KAISHA, LTD. (JP) | 2007-02-27 | — | — | US | disclosed |
| EP-1134214-A1 | PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2001-09-19 | — | — | EP | disclosed |