Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327993 | 0.81 | TDP1 (0.40) | LIPGALOX5PTGS2PPARA | |
| SCHEMBL29505758 | 0.79 | TAAR1 (0.41) | IDO1IDO2 | |
| SCHEMBL16039155 | 0.77 | AGTR2 (0.41) | — | |
| SCHEMBL1024526 | 0.77 | LIPG (0.59) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL3801556 | 0.77 | LIPG (0.47) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL9619382 | 0.75 | LIPG (0.62) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL1921650 | 0.75 | LIPG (0.62) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL8157124 | 0.75 | LIPG (0.62) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL196217 | 0.75 | LIPG (0.62) | LIPGNR1H2NR1H3ALOX5PTGS2 | |
| SCHEMBL11663988 | 0.75 | LIPG (0.62) | LIPGNR1H2NR1H3ALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007517782-A | — | — | 2007-07-05 | — | — | JP | claimed |
| EP-1694123-A1 | TOPICAL FORMULATIONS COMPRISING A 1-N-ARYLPYRAZOLE DERIVATIVE AND A FORMAMIDINE | Merial Ltd. (US) | 2006-08-30 | — | — | EP | claimed |
| WO-2005058038-A1 | TOPICAL FORMULATIONS COMPRISING A 1-N-ARYLPYRAZOLE DERIVATIVE AND A FORMAMIDINE | MERIAL LIMITED (US) | 2005-06-30 | — | — | WO | claimed |