Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.41 |
| ▸ | BRS3 | P32247 | 9/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16039157 | 0.78 | DHODH (0.38) | AGTR2AGTR1BRS3 | |
| SCHEMBL14918727 | 0.78 | HNF4A (0.49) | — | |
| SCHEMBL27892555 | 0.77 | SMN1; SMN2 (0.45) | PTPN11 | |
| SCHEMBL8674372 | 0.77 | MYC (0.44) | PTPN11 | |
| SCHEMBL14919171 | 0.76 | MEN1 (0.51) | — | |
| SCHEMBL16037019 | 0.75 | ALDH1A1 (0.43) | — | |
| SCHEMBL25181813 | 0.74 | FOLH1 (0.53) | AGTR2AGTR1BRS3PTPN11 | |
| SCHEMBL1535274 | 0.74 | RAB9A (0.46) | BRS3 | |
| SCHEMBL38662910 | 0.73 | BID (0.52) | — | |
| SCHEMBL3706715 | 0.73 | BID (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | ELI LILLY AND COMPANY | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140275049-A1 | SUBSTITUTED PYRAZOLE ANALOGS As RAR ANTAGONISTS | RARB, RARA, RARG | AGTR2 377/4885AGTR1 270/4885BRS3 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.