SCHEMBL5584253

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5584314	0.82	F2RL3 (0.40)	F2RL3CES2MEN1KMT2ACYP3A4
	SCHEMBL5584393	0.82	MKNK1 (0.43)	F2RL3MKNK1
	SCHEMBL5584518	0.78	ALDH1A1 (0.41)	F2RL3CYP3A4TP53TDP1MKNK1
	SCHEMBL5585409	0.77	F2RL3 (0.39)	F2RL3CES2MEN1KMT2ACYP3A4
	SCHEMBL2268224	0.76	SLC22A12 (0.47)	CES2MAOASLC22A12
	SCHEMBL5584685	0.74	F2RL3 (0.42)	F2RL3CES2MEN1KMT2ACYP3A4
	SCHEMBL428470	0.71	F2RL3 (0.41)	F2RL3CES2MEN1KMT2ACYP3A4
	SCHEMBL20153640	0.71	AHR (0.41)	MEN1KMT2AMAPTKDM4ECYP2C9
	SCHEMBL5584352	0.69	F2RL3 (0.42)	F2RL3CES2MEN1KMT2ACYP3A4
	SCHEMBL5585309	0.69	F2RL3 (0.45)	F2RL3CES2MEN1KMT2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.