SCHEMBL5584650

SCHEMBL5584650

CC(C)O[SiH](N)c1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TAAR1 Q96RJ0 5/20 0.32
SLC6A2 P23975 2/20 0.32
MAOA P21397 2/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
CYP2A6 P11509 1/20 0.32
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2C P18825 1/20 0.31
LMNA P02545 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 1/20 0.31
TSHR P16473 1/20 0.31
PTGS1 P23219 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7051181 0.76 ALDH1A1 (0.35) ALDH1A1L3MBTL1TAAR1SLC6A2MAOA
SCHEMBL3888063 0.76 ALDH1A1 (0.35) ALDH1A1L3MBTL1TAAR1SLC6A2MAOA
SCHEMBL706200 0.74 ALDH1A1 (0.34) ALDH1A1L3MBTL1LMNAKDM4ETSHR
SCHEMBL17200632 0.73 CA4 (0.38) ALDH1A1LMNAKDM4ETSHRPTGS1
SCHEMBL706901 0.73 ALDH1A1 (0.33) ALDH1A1L3MBTL1TSHR
SCHEMBL27639855 0.72 TAAR1 (0.38) ALDH1A1L3MBTL1TAAR1SLC6A2MAOA
SCHEMBL23174996 0.71 ALDH1A1 (0.32) ALDH1A1L3MBTL1
SCHEMBL703370 0.70 MAPK1 (0.32) ALDH1A1L3MBTL1
SCHEMBL707825 0.70 TSHR (0.32) ALDH1A1L3MBTL1TAAR1SLC6A2MAOA
SCHEMBL2424489 0.69 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9321017-B2 Gas-separation membrane NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2016-04-26 US disclosed
US-20150033945-A1 GAS-SEPARATION MEMBRANE NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) 2015-02-05 US disclosed
US-8734574-B2 Gas separation membrane IBIDEN CO., LTD. (JP) 2014-05-27 US disclosed
US-20120202953-A1 GAS SEPARATION MEMBRANE NATIONAL UNIVERSITY CORP KYOTO INSTITUTE OF TECH (JP) 2012-08-09 US disclosed
EP-2471592-A1 GAS SEPARATION MEMBRANE Ibiden Co., Ltd. (JP) 2012-07-04 EP disclosed
EP-1792928-A1 MULTIBRANCHED POLYIMIDE HYBRID MATERIAL NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) 2007-06-06 EP disclosed