SCHEMBL3888063

SCHEMBL3888063

CC(C)O[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PDCD1 Q15116 1/20 0.31
CD274 Q9NZQ7 1/20 0.31
MAOA P21397 2/20 0.31
LMNA P02545 1/20 0.31
CA4 P22748 1/20 0.31
TRPA1 O75762 2/20 0.30
KMT2A Q03164 1/20 0.30
TAAR1 Q96RJ0 4/20 0.30
SLC6A2 P23975 2/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
CYP2A6 P11509 1/20 0.30
ADORA2A P29274 1/20 0.30
ADORA1 P30542 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23701156 0.81 TSHR (0.33) TSHRTDP1
SCHEMBL23701039 0.81 TRPA1 (0.32) TDP1TRPA1TAAR1
SCHEMBL7051181 0.80 ALDH1A1 (0.35) ALDH1A1L3MBTL1TSHRTDP1PDCD1
SCHEMBL3179891 0.79 HCAR2 (0.38) ALDH1A1LMNATRPA1TAAR1
SCHEMBL3301398 0.79 CA4 (0.32) TSHRCA4
SCHEMBL706200 0.78 ALDH1A1 (0.34) ALDH1A1L3MBTL1TSHRTDP1PDCD1
SCHEMBL23449018 0.78 MAPT (0.35) TSHRMAOALMNATRPA1TAAR1
SCHEMBL708401 0.78 TRPA1 (0.32) ALDH1A1L3MBTL1TRPA1
SCHEMBL706901 0.76 ALDH1A1 (0.33) ALDH1A1L3MBTL1TSHRTDP1
SCHEMBL5584650 0.76 ALDH1A1 (0.33) ALDH1A1L3MBTL1TSHRMAOALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119608184-A Ball-milling catalytic hydrosilylation reaction method and catalyst used in same 浙江大学 2025-03-14 CN disclosed
US-11851450-B2 Monosubstituted diphenylsilanes and synthesis thereof HONEYWELL FEDERAL MANUFACTURING & TECHNOLOGIES, LLC (US) 2023-12-26 US disclosed
US-11807758-B2 Siloxane polymer and method of producing siloxane polymer JNC CORPORATION (JP) 2023-11-07 US disclosed
US-11760839-B2 Processes for making polysiloxazanes and using same for producing amino-functional polyorganosiloxanes DOW SILICONES CORPORATION (US) 2023-09-19 US disclosed
CN-114369097-B Heteroaromatic AhR inhibitors 山东轩竹医药科技有限公司 2023-07-14 CN disclosed
US-20230151033-A1 MONOSUBSTITUTED DIPHENYLSILANES AND SYNTHESIS THEREOF HONEYWELL FEDERAL MANUFACTURING & TECHNOLOGIES, LLC 2023-05-18 US disclosed
US-20210238419-A1 SILOXANE POLYMER AND METHOD OF PRODUCING SILOXANE POLYMER JNC CORPORATION (JP) 2021-08-05 US disclosed
EP-3508473-B1 METHOD FOR PRODUCING CARBAMIC ACID ESTER AIST (JP) 2021-05-26 EP disclosed
US-10752579-B2 Production method of carbamic acid ester NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2020-08-25 US disclosed
US-10683288-B2 Epothilone B and dictyostatin analogs, their preparation and use THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2020-06-16 US disclosed
EP-1375597-A1 RADIATION-SENSITIVE COMPOSITION CHANGING IN REFRACTIVE INDEX AND UTILIZATION THEREOF JSR Corporation (JP) 2004-01-02 EP disclosed
US-6652608-B1 Fuel compositions exhibiting improved fuel stability OCTANE INTERNATIONAL, LTD. 2003-11-25 US disclosed
EP-1359166-A1 OLEFIN POLYMERIZATION CATALYST, CATALYST COMPONENT FOR OLEFIN POLYMERIZATION, METHOD OF STORING THESE, AND PROCESS FOR PRODUCING OLEFIN POLYMER Sunallomer Ltd (JP) 2003-11-05 EP disclosed
US-20030171468-A1 Radiation-sensitive composition changing in refractive index and utilization thereof JSR CORPORATION (JP) 2003-09-11 US disclosed
EP-1258035-A1 PROCESS FOR WAFER LEVEL TREATMENT TO REDUCE STICTION AND PASSIVATE MICROMACHINED SURFACES AND COMPOUNDS USED THEREFOR ANALOG DEVICES, INC. (US) 2002-11-20 EP disclosed
WO-2001057920-A1 PROCESS FOR WAFER LEVEL TREATMENT TO REDUCE STICTION AND PASSIVATE MICROMACHINED SURFACES AND COMPOUNDS USED THEREFOR ANALOG DEVICES, INC. (US) 2001-08-09 WO disclosed
US-6037277-A ATMOSPHERIC CONTROLLING TO PREVENT EVAPORATION AND CONDENSATION TEXAS INSTRUMENTS INCORPORATED (US) 2000-03-14 US disclosed
US-4388449-A THERMOPLASTIC, DIELECTRICS, HOLD OUT AGENTS FOR HEAT RECOVERABLE MATERIALS RAYCHEM LIMITED (GB) 1983-06-14 US disclosed
WO-1982001710-A1 ALUMINUM CATALYZED SILICON ALKOXIDE-EPOXY COMPOSITIONS DOW CORNING (US) 1982-05-27 WO disclosed
US-4265801-A FIREPROOF DIELECTRIC SACKETS FOR WIRES ETC. RAYCHEM LIMITED (GB) 1981-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10683288-B2 Epothilone B and dictyostatin analogs, their preparation and use DHPS, EPOR, THPO ALDH1A1 4231/4885L3MBTL1 1348/4885TSHR 2220/4885
US-11760839-B2 Processes for making polysiloxazanes and using same for producing amino-functional polyorganosiloxanes PPOX, DAO, AOX1 ALDH1A1 687/4885L3MBTL1 2341/4885TSHR 4492/4885
US-11851450-B2 Monosubstituted diphenylsilanes and synthesis thereof DERA, SELENOI, TST ALDH1A1 525/4885L3MBTL1 2157/4885TSHR 3297/4885
US-10752579-B2 Production method of carbamic acid ester CA2, CA7, CA4 ALDH1A1 3215/4885L3MBTL1 3678/4885TSHR 1277/4885
US-20230151033-A1 MONOSUBSTITUTED DIPHENYLSILANES AND SYNTHESIS THEREOF DERA, SELENOI, TST ALDH1A1 525/4885L3MBTL1 2157/4885TSHR 3297/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.