SCHEMBL2424489

SCHEMBL2424489

N[SiH](O[SiH3])c1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17200632 0.74 CA4 (0.38) TSHR
SCHEMBL30529945 0.72 LTA4H (0.32) TSHR
SCHEMBL35818 0.72 LTA4H (0.32) TSHR
SCHEMBL573507 0.70 LTA4H (0.30) TSHR
SCHEMBL10699684 0.70 LTA4H (0.30) TSHR
SCHEMBL28241337 0.69 LOXL2 (0.33)
SCHEMBL28112919 0.69 ALDH1A1 (0.34) TSHR
SCHEMBL1602999 0.69 TDP1 (0.30)
SCHEMBL5584650 0.69 ALDH1A1 (0.33) TSHR
SCHEMBL5430516 0.68 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024005163-A1 ANTIBACTERIAL COMPOSITION 株式会社キャスティングイン 2024-01-04 WO disclosed
US-8022006-B2 Catalyst nanoparticle THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2011-09-20 US disclosed
US-7858550-B2 depositing a self-assembled monolayer on a substrate, depositing a catalyst nanoparticle covalently bonded to a ligand, and a material capable of binding to the self-assembled monolayer; electrochemically modifying a conductive glassy carbon electrode substrate THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE NAVY 2010-12-28 US disclosed
US-7803498-B2 Materials and structures thereof useful as electrocatalysts THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-09-28 US disclosed
US-20080050641-A1 Catalyst nanoparticle NAVY, THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE 2008-02-28 US disclosed
US-20080050642-A1 Materials and structures thereof useful as electrocatalysts NAVY, THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE 2008-02-28 US disclosed
US-20080051281-A1 Method of making a nanostructured electrode THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE NAVY 2008-02-28 US disclosed
US-5286890-A Aromatic amine terminated silicone monomers, oligomers, and polymers therefrom HUGHES AIRCRAFT COMPANY (US) 1994-02-15 US disclosed