Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 6/20 | 0.40 |
| ▸ | MMP2 | P08253 | 6/20 | 0.40 |
| ▸ | MMP9 | P14780 | 6/20 | 0.40 |
| ▸ | MMP13 | P45452 | 6/20 | 0.40 |
| ▸ | MMP8 | P22894 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | FLT4 | P35916 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142857 | 1.00 | ALDH1A1 (0.42) | ALDH1A1GLAEGFRERBB2MMP1 | |
| SCHEMBL5585265 | 0.87 | CNR1 (0.41) | ALDH1A1GLAEGFRERBB2MMP1 | |
| SCHEMBL5144983 | 0.87 | CNR1 (0.41) | ALDH1A1GLAEGFRERBB2MMP1 | |
| SCHEMBL5585266 | 0.87 | CNR1 (0.41) | ALDH1A1GLAEGFRERBB2MMP1 | |
| Hydrochloric Acid SCHEMBL5166456 | 0.71 | LMNA (0.40) | ALDH1A1EGFRLMNAFLT1KDR | |
| SCHEMBL5318640 | 0.71 | MEN1 (0.46) | ALDH1A1GLAEGFRERBB2MMP1 | |
| SCHEMBL3525482 | 0.69 | CNR1 (0.44) | MMP2LMNAL3MBTL1CNR1 | |
| SCHEMBL3521154 | 0.65 | CNR1 (0.51) | ALDH1A1EGFRERBB2LMNAKMT2A | |
| SCHEMBL29244487 | 0.63 | FLT1 (0.54) | MMP1MMP2MMP9MMP13MMP8 | |
| SCHEMBL13500866 | 0.62 | CYP1A2 (0.40) | EGFRERBB2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | claimed |
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
| US-20070105914-A1 | Substituted sulfonamides | MERCK SHARP & DOHME CORP. | 2007-05-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070105914-A1 | Substituted sulfonamides | CNR2, CNR1, FAAH | ALDH1A1 3915/4885GLA 2014/4885EGFR 1653/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.