Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PLK1 | P53350 | 7/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250247 | 0.77 | HDAC6 (0.80) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL4555705 | 0.76 | HDAC8 (0.64) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL4672838 | 0.75 | CA1 (0.57) | HPGDTSHRHTTSMN1; SMN2CA2 | |
| SCHEMBL5909363 | 0.73 | HDAC8 (0.83) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL31627721 | 0.73 | TSHR (0.52) | TSHRSMN1; SMN2CA2 | |
| SCHEMBL4141704 | 0.72 | KMT2A (0.56) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL328702 | 0.72 | HDAC6 (0.67) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL16521645 | 0.72 | HDAC8 (0.54) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL21968466 | 0.72 | HDAC8 (0.52) | HDAC8HDAC6HDAC2PLAUHPGD | |
| SCHEMBL4478521 | 0.71 | HDAC8 (0.60) | HDAC8HDAC6HDAC2PLAUHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | DYNAMIS THERAPEUTICS, INC. | 2007-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070065443-A1 | Fructoseamine 3 kinase and the formation of collagen and elastin | FN3K, PDXK, COLGALT1 | HDAC8 3072/4885HDAC6 3324/4885HDAC2 2294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.