Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 1/20 | 0.39 |
| ▸ | MRE11 | P49959 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | GIPR | P48546 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.37 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000111 | 1.00 | CPB1 (0.39) | CPB1MRE11RAB9AMEN1KMT2A | |
| SCHEMBL5585253 | 0.92 | CA1 (0.41) | CPB1MRE11RAB9AMEN1KMT2A | |
| SCHEMBL5585395 | 0.90 | ALDH1A1 (0.41) | CPB1MEN1KMT2ATRPA1ALDH1A1 | |
| SCHEMBL5585653 | 0.90 | RAB9A (0.41) | MRE11RAB9AMEN1KMT2AGAA | |
| SCHEMBL5999050 | 0.90 | HDAC3 (0.48) | MRE11RAB9AMEN1KMT2ATRPA1 | |
| SCHEMBL5585688 | 0.89 | RAB9A (0.40) | MRE11RAB9AMEN1KMT2AGAA | |
| Hydrochloric Acid SCHEMBL5585772 | 0.89 | RAB9A (0.40) | MRE11RAB9AMEN1KMT2AGAA | |
| SCHEMBL5585392 | 0.89 | RXRA (0.42) | CPB1MRE11RAB9AMEN1KMT2A | |
| SCHEMBL6000638 | 0.89 | RXRA (0.42) | CPB1MRE11RAB9AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5585448 | 0.88 | RXRA (0.41) | CPB1MRE11RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163952-B2 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| US-20050065196-A1 | Azole compound and medicinal use thereof | JAPAN TOBACCO INC. (JP) | 2005-03-24 | — | — | US | disclosed |
| EP-1452530-A1 | AZOLE COMPOUND AND MEDICINAL USE THEREOF | JAPAN TOBACCO INC. (JP) | 2004-09-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065196-A1 | Azole compound and medicinal use thereof | PTPN7, PTPN1, PTPN5 | CPB1 1778/4885MRE11 4833/4885RAB9A 1736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.