SCHEMBL5586060

SCHEMBL5586060

NNc1cccc2sc(C(=O)c3ccccc3)nc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
PKM P14618 3/20 0.42
HSD17B1 P14061 2/20 0.40
HSD17B2 P37059 2/20 0.40
SCD O00767 1/20 0.39
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
CDK5 Q00535 2/20 0.39
CDK5R1 Q15078 2/20 0.39
CCNA2 P20248 2/20 0.38
CDK2 P24941 2/20 0.38
MAPK14 Q16539 2/20 0.38
RET P07949 1/20 0.38
FLT1 P17948 1/20 0.38
KDR P35968 1/20 0.38
MAPT P10636 4/20 0.37
TDP1 Q9NUW8 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9183949 0.78 HSD17B1 (0.43) GAAPKMHSD17B1HSD17B2SCD
SCHEMBL28901461 0.78 PDE10A (0.47) GAAPKMHSD17B1HSD17B2SCD
SCHEMBL24751 0.72 HSD17B1 (0.62) PKMHSD17B1HSD17B2SCDMEN1
Bromide SCHEMBL28862925 0.71 HSD17B1 (0.61) PKMHSD17B1HSD17B2SCDMEN1
SCHEMBL8404889 0.70 HSD17B1 (0.49) GAAPKMHSD17B1HSD17B2MEN1
SCHEMBL4538101 0.68 KMT2A (0.61) GAAMEN1KMT2AMAPK14MAPT
SCHEMBL8404893 0.68 HSD17B1 (0.47) GAAPKMHSD17B1HSD17B2MEN1
SCHEMBL8403887 0.68 HSD17B1 (0.49) GAAPKMHSD17B1HSD17B2MEN1
SCHEMBL28885770 0.67 ALDH1A1 (0.55) GAAPKMMEN1KMT2ANPC1
SCHEMBL28990422 0.66 LMNA (0.56) GAAPKMMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP claimed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 WO claimed
US-20050042758-A1 Leak detection method using microencapsulated dye precursor HONEYWELL CORPORATION 2005-02-24 US claimed
CN-101003499-B Novel color former and recording material ASAHI CHEMICAL IND 2011-01-19 CN disclosed
CN-100532120-C Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO LTD (JP) 2009-08-26 CN disclosed
CN-101003499-A Novel color former and recording material ASAHI CHEMICAL IND (JP) 2007-07-25 CN disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
CN-1303064-C Novel color-developing composition and recording material ASAHI CHEMICAL IND (JP) 2007-03-07 CN disclosed
EP-1656551-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR Honeywell International Inc. (US) 2006-05-17 EP disclosed
CN-1644393-A Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO LTD (JP) 2005-07-27 CN disclosed
US-6881810-B2 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2005-04-19 US disclosed
WO-2005019816-A1 LEAK DETECTION METHOD USING MICROENCAPSULATED DYE PRECURSOR HONEYWELL INTERNATIONAL, INC. (US) 2005-03-03 WO disclosed
US-20050042758-A1 Leak detection method using microencapsulated dye precursor HONEYWELL CORPORATION 2005-02-24 US disclosed
US-20040121155-A1 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-06-24 US disclosed
CN-1496346-A Novel color-developing composition and recording material 旭化成株式会社 2004-05-12 CN disclosed
EP-1382385-A1 Microcapsule and process for manufacturing the same FUJI PHOTO FILM CO., LTD. (JP) 2004-01-21 EP disclosed
US-6245499-B1 PHOTOSENSITIVE LAYER(S) COMPRISING AN ORGANIC SILVER SALT, A SILVER HALIDE, A REDUCING AGENT, A HYDRAZINE DERIVATIVE AND A SENSITIZING DYE; HIGH DMAX, HIGH CONTRAST, COLOR RESOLUTION, IMAGE QUALITY, PRINTING PLATES FUJI PHOTO FILM CO., LTD. (JP) 2001-06-12 US disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed