Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | GALK1 | P51570 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3645705 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL5585773 | 0.85 | CTSK (0.48) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL21198730 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL11609600 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL29222624 | 0.71 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTRAB9ANPC1 | |
| SCHEMBL29642581 | 0.71 | CTSL (0.60) | CTSLCTSK | |
| SCHEMBL1756728 | 0.71 | CCR1 (0.51) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL11608129 | 0.70 | HSD17B10 (0.59) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL27797797 | 0.69 | CTSL (0.42) | ALDH1A1L3MBTL1MAPTHTTKMT2A | |
| SCHEMBL1976429 | 0.69 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740584-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105802-A1 | FUSED QUINOLINE DERIVATIVE AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-11-10 | — | — | WO | disclosed |