⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712164 | 0.93 | — | — | |
| SCHEMBL9712178 | 0.91 | — | — | |
| SCHEMBL6762569 | 0.90 | — | — | |
| SCHEMBL5585792 | 0.84 | — | — | |
| SCHEMBL6685764 | 0.83 | OPRM1 (0.30) | — | |
| SCHEMBL6684870 | 0.79 | LTA4H (0.33) | — | |
| SCHEMBL5585758 | 0.77 | — | — | |
| SCHEMBL5585337 | 0.76 | — | — | |
| SCHEMBL5585657 | 0.76 | — | — | |
| SCHEMBL5585716 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836238-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | Bridgestone Corporation (JP) | 2007-09-26 | — | — | EP | claimed |
| WO-2006076629-A1 | FUNCTIONALIZED POLYMERS AND IMPROVED TIRES THEREFROM | BRIDGESTONE CORPORATION (JP) | 2006-07-20 | — | — | WO | claimed |
| EP-0816359-B1 | 4-Amino-2-ureido-pyrimidine-5-carboxamides, processes for their preparation, medicaments containing these compounds, and their use | AVENTIS PHARMA GMBH (DE) | 2004-11-03 | — | — | EP | claimed |
| US-5773447-A | 4-AMINO-2-UREIDOPYRIMIDINE-5-CARBOXAMIDE FORMED BY AMIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | claimed |
| EP-0816359-A1 | 4-Amino-2-ureido-pyrimidine-5-carboxamides, processes for their preparation, medicaments containing these compounds, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-07 | — | — | EP | claimed |
| EP-4608452-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | Eisai R&D Management Co., Ltd. (JP) | 2025-09-03 | — | — | EP | disclosed |
| EP-4551580-A2 | CRYSTALLINE MONOMERS FOR PREPARING ANTISENSE OLIGONUCLEOTIDES AND METHODS OF THEIR PREPARATION AND USE | Eisai R&D Management Co., Ltd. (JP) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025095980-A1 | ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-05-08 | — | — | WO | disclosed |
| EP-4291552-B1 | MODULATORS OF COMPLEX I | BOEHRINGER INGELHEIM INT (DE) | 2025-04-09 | — | — | EP | disclosed |
| US-20250092392-A1 | ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2025-03-20 | — | — | US | disclosed |
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |
| WO-2024092256-A2 | PEPTIDE-ANTISENSE OLIGONUCLEOTIDES AND THEIR USE FOR TREATMENT OF NEURODEGENERATIVE DISORDERS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2024-05-02 | — | — | WO | disclosed |
| WO-2000012563-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF OLIGONUCLEOTIDES INCORPORATING 2-AMINOADENOSINE | ISIS PHARMACEUTICALS, INC. (US) | 2000-03-09 | — | — | WO | disclosed |
| US-5773447-A | 4-AMINO-2-UREIDOPYRIMIDINE-5-CARBOXAMIDE FORMED BY AMIDATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | disclosed |
| EP-0816359-A1 | 4-Amino-2-ureido-pyrimidine-5-carboxamides, processes for their preparation, medicaments containing these compounds, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-01-07 | — | — | EP | disclosed |
| US-4282201-A | Pharmaceutical comprising drug and polymer | ALZA CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4279918-A | ANTIDEPRESSANTS, STIMULANTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK G.M.B.H. (DE) | 1981-07-21 | — | — | US | disclosed |
| US-4259102-A | Composition comprising useful agent such as fertilizers, housed in heterocyclic polymer | ALZA CORPORATION (US) | 1981-03-31 | — | — | US | disclosed |
| US-4246397-A | Polymers comprising heterocyclic system | ALZA CORPORATION (US) | 1981-01-20 | — | — | US | disclosed |
| US-4211867-A | ANTISECRETORY AGENTS, HYPOGLYCEMIC AGENTS, ANTIARRHYTHMIA AGENTS | MCNEIL LABORATORIES, INCORPORATED (US) | 1980-07-08 | — | — | US | disclosed |