Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL193627 | 0.95 | PABPC1 (0.40) | PABPC1APOBEC3AEIF4HAPOBEC3GLMNA | |
| Hydrochloric Acid SCHEMBL3780200 | 0.95 | PABPC1 (0.40) | PABPC1APOBEC3AEIF4HAPOBEC3GLMNA | |
| Bromide SCHEMBL918125 | 0.88 | MEN1 (0.38) | LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL210855 | 0.88 | MEN1 (0.38) | LMNAMAPTMEN1KMT2A | |
| SCHEMBL1226951 | 0.86 | MEN1 (0.39) | LMNAMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5586444 | 0.85 | S1PR3 (0.38) | PABPC1APOBEC3AEIF4HAPOBEC3GLMNA | |
| SCHEMBL22335456 | 0.84 | S1PR3 (0.38) | PABPC1APOBEC3AEIF4HAPOBEC3GFDPS | |
| SCHEMBL193018 | 0.83 | GSK3B (0.35) | PABPC1APOBEC3AEIF4HAPOBEC3GFDPS | |
| SCHEMBL19219090 | 0.83 | MAPT (0.42) | PABPC1APOBEC3AEIF4HAPOBEC3GLMNA | |
| Bromide SCHEMBL8457516 | 0.82 | FDPS (0.45) | PABPC1APOBEC3AEIF4HAPOBEC3GLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1745327-A1 | MULTICOLOR DISPLAY ELEMENT | Ricoh Company, Ltd. (JP) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005111709-A1 | MULTICOLOR DISPLAY ELEMENT | RICOH COMPANY, LTD. (JP) | 2005-11-24 | — | — | WO | disclosed |