SCHEMBL5587942

SCHEMBL5587942

CCc1ccc(OC(=O)O)c(O)c1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 3/20 0.39
PDE4B Q07343 3/20 0.39
PDE4C Q08493 3/20 0.39
PDE4D Q08499 3/20 0.39
KDM4E B2RXH2 3/20 0.37
GAA P10253 2/20 0.37
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
RCE1 Q9Y256 1/20 0.37
GABRA1 P14867 1/20 0.36
GABRB2 P47870 1/20 0.36
CNR2 P34972 1/20 0.36
UCHL1 P09936 1/20 0.35
USP5 P45974 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589366 0.90 PRKCI (0.38) PDE4APDE4BPDE4CPDE4DKDM4E
SCHEMBL5587746 0.87 CNR2 (0.40) KDM4EMAPTALDH1A1CNR2ESR1
SCHEMBL5587781 0.81 PDE4A (0.41) PDE4APDE4BPDE4CPDE4DKDM4E
SCHEMBL1839146 0.81 MAPT (0.39) KDM4EGAAMAPTSMN1; SMN2NPC1
SCHEMBL5587373 0.81 ESR1 (0.40) PDE4APDE4BPDE4CPDE4DKDM4E
SCHEMBL5588866 0.81 KDM4E (0.38) PDE4APDE4BPDE4CPDE4DKDM4E
SCHEMBL5587866 0.77 GABRA1 (0.36) KDM4EGAAMAPTSMN1; SMN2ALDH1A1
SCHEMBL5589787 0.77 GABRA1 (0.36) MAPTGABRA1GABRB2
SCHEMBL5588022 0.76 LTB4R (0.38) PDE4APDE4BPDE4CPDE4DCNR2
SCHEMBL9423903 0.76 HDAC4 (0.47) PDE4APDE4BPDE4CPDE4DKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 PDE4A 4875/4885PDE4B 4878/4885PDE4C 4881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.