SCHEMBL5589891

SCHEMBL5589891

Cc1ccc(OC(=O)O)c(O)c1CCCCl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
CYP2C9 P11712 4/20 0.33
PTPN1 P18031 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
LMNA P02545 2/20 0.32
NPC1 O15118 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
RAB9A P51151 1/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
RXRG P48443 1/20 0.32
MRGPRX4 Q96LA9 1/20 0.32
SMN1; SMN2 Q16637 2/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP1A2 P05177 2/20 0.31
PPARG P37231 2/20 0.31
PPARA Q07869 2/20 0.31
MAPT P10636 2/20 0.31
TTR P02766 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5678240 0.86 NCEH1 (0.40) TSHRCYP2C9LMNANPC1PKM
SCHEMBL5681379 0.85 ALOX5 (0.43) PPARGPPARA
SCHEMBL5587875 0.84 LDHA (0.41) CYP2C9LMNACYP1A2PPARGPPARA
SCHEMBL5588144 0.82 SLC22A12 (0.32) TSHRSLC22A12HTR2B
SCHEMBL5589610 0.82 TSHR (0.37) TSHRCYP1A2PPARGPPARAMAPT
SCHEMBL5195611 0.81 NCEH1 (0.34) TSHRCYP2C9PTPN1SLC22A12PKM
SCHEMBL5588099 0.79 NCEH1 (0.31)
SCHEMBL5589679 0.75 TYR (0.36) TSHRCYP1A2PPARGPPARAMAPT
SCHEMBL6232728 0.75 AKR1C2 (0.39) TSHRLMNANPC1HTTRAB9A
SCHEMBL6230577 0.75 CYP1A2 (0.40) TSHRCYP2C9LMNACYP1A2PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885CYP2C9 3617/4885PTPN1 4679/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.