SCHEMBL5589911

SCHEMBL5589911

Cc1c(C)c(-c2ccccc2)c(C(=O)O)c(O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LDHA P00338 3/20 0.45
LDHB P07195 3/20 0.45
PDE10A Q9Y233 3/20 0.42
TSHR P16473 1/20 0.42
HNF4A P41235 1/20 0.42
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
DHODH Q02127 2/20 0.41
FABP3 P05413 3/20 0.40
FABP4 P15090 3/20 0.40
LMNA P02545 3/20 0.40
PRNP P04156 1/20 0.40
PPARG P37231 1/20 0.40
RXFP1 Q9HBX9 1/20 0.40
NR2E3 Q9Y5X4 1/20 0.40
NCOR2 Q9Y618 1/20 0.40
SENP1 Q9P0U3 1/20 0.39
PDE4A P27815 1/20 0.39
PDE4B Q07343 1/20 0.39
PDE4C Q08493 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5588862 0.83 LDHA (0.41) LDHALDHBPDE10ATSHRHNF4A
SCHEMBL10832124 0.82 PDE10A (0.50) PDE10ATSHRKMT2AMEN1DHODH
SCHEMBL27663766 0.81 PDE10A (0.49) PDE10ATSHRKMT2AMEN1DHODH
SCHEMBL27816594 0.80 PDE10A (0.47) PDE10ATSHRKMT2AMEN1DHODH
SCHEMBL18705323 0.80 HNF4A (0.52) PDE10AHNF4AKMT2ADHODHFABP3
SCHEMBL5586755 0.79 LDHA (0.51) LDHALDHBPDE10ATSHRKMT2A
SCHEMBL29042678 0.79 PDE10A (0.46) PDE10ATSHRKMT2AMEN1DHODH
SCHEMBL5588526 0.78 LDHA (0.44) LDHALDHBPPARGKDM4EALDH1A1
SCHEMBL5589126 0.78 SENP1 (0.58) KMT2AMEN1LMNASENP1PDE4A
SCHEMBL28248289 0.78 SENP1 (0.58) HNF4AKMT2AMEN1LMNASENP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 LDHA 320/4885LDHB 486/4885PDE10A 4804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.