Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | AURKA | O14965 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
| ▸ | IKBKB | O14920 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.30 |
| ▸ | PRKCG | P05129 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5590774 | 1.00 | MAPT (0.35) | MAPTRAB9AALDH1A1GAAHTT | |
| SCHEMBL29134217 | 0.79 | ALDH1A1 (0.50) | MAPTRAB9AALDH1A1GAAHTT | |
| SCHEMBL1943629 | 0.79 | ALDH1A1 (0.50) | MAPTRAB9AALDH1A1GAANPC1 | |
| SCHEMBL1512700 | 0.78 | — | — | |
| SCHEMBL10948448 | 0.77 | GOT1 (0.31) | — | |
| SCHEMBL27831600 | 0.75 | GOT1 (0.30) | — | |
| SCHEMBL11136809 | 0.74 | AURKA (0.56) | RAB9AGAANPC1AURKAATM | |
| SCHEMBL285342 | 0.73 | TRPA1 (0.38) | MEN1KMT2A | |
| SCHEMBL27523150 | 0.69 | — | — | |
| SCHEMBL472841 | 0.69 | NFE2L2 (0.34) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4388079-A | QUATERNARY SALT OF AN ANIONIC AND A CATIONIC DYES; WHITENERS; PAPERMAKING; TEXTILES; PLASTICS | SHOWA KAGAKU KOGYO CO., LTD. (JP) | 1983-06-14 | — | — | US | claimed |
| US-4374643-A | Color salts of basic dyes with acidic optical brighteners of stilbene type | SHOWA KAGAKU KOGYO CO., LTD (JP) | 1983-02-22 | — | — | US | claimed |
| US-20070085026-A1 | Invisible eyemark and method for orienting squeeze tube | TUBEDEC, LLC | 2007-04-19 | — | — | US | disclosed |
| US-20050230662-A1 | Diaminostilbene derivatives | KIMURA KEIZO | 2005-10-20 | — | — | US | disclosed |
| US-6919452-B1 | A 4,4'-bis(1,3,5-triazinylamino)stilbene-2,2'- disulfonic acid derivatives as fluorescent brightening agents, water soluble | FUJI PHOTO FILM CO., LTD (JP) | 2005-07-19 | — | — | US | disclosed |
| EP-0029003-B1 | SALTS OF CATIONIC BRIGHTENERS, THEIR PREPARATION AND THEIR USE ON ORGANIC MATERIALS AS WELL AS THEIR CONCENTRATED AQUEOUS SOLUTIONS | CIBA-GEIGY AG (CH) | 1984-12-05 | — | — | EP | disclosed |
| US-4433975-A | HETEROCYCLIC QUATERNARY AMMONIUM PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-28 | — | — | US | disclosed |
| US-4432886-A | 2-FURANYLBENZIMIDAZOLE, OR 2-AZOLYLBENZIMIDAZOLE, OR 2-STILBENYLBENZIMIDAZOLE, OR 2,5-(BENZIMIDAZOLYL)FURAN PHOSPHATES | CIBA-GEIGY CORPORATION (US) | 1984-02-21 | — | — | US | disclosed |
| US-4388079-A | QUATERNARY SALT OF AN ANIONIC AND A CATIONIC DYES; WHITENERS; PAPERMAKING; TEXTILES; PLASTICS | SHOWA KAGAKU KOGYO CO., LTD. (JP) | 1983-06-14 | — | — | US | disclosed |
| US-4384121-A | WATER SOLUBLE | CIBA-GEIGY CORPORATION (US) | 1983-05-17 | — | — | US | disclosed |
| US-4374643-A | Color salts of basic dyes with acidic optical brighteners of stilbene type | SHOWA KAGAKU KOGYO CO., LTD (JP) | 1983-02-22 | — | — | US | disclosed |
| EP-0029003-A2 | Salts of cationic brighteners, their preparation and their use on organic materials as well as their concentrated aqueous solutions | CIBA-GEIGY AG (CH) | 1981-05-20 | — | — | EP | disclosed |
| US-4263431-A | ARYL QUATERNARY AMINE PHOSPHONATE DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050230662-A1 | Diaminostilbene derivatives | SLC35B2, ARSA, SLC9B2 | MAPT 4056/4885RAB9A 4043/4885ALDH1A1 564/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.