SCHEMBL5590802

SCHEMBL5590802

Cc1ccc(-c2ccc(C)c(C)c2O)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.42
POLB P06746 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
CTDSP1 Q9GZU7 1/20 0.41
CNR1 P21554 1/20 0.41
CNR2 P34972 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
MAPT P10636 1/20 0.41
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
TDP2 O95551 1/20 0.39
NSD2 O96028 1/20 0.39
HSP90AA1 P07900 1/20 0.39
PAX8 Q06710 1/20 0.39
SENP1 Q9P0U3 1/20 0.39
PTGS2 P35354 4/20 0.38
PTGS1 P23219 2/20 0.37
HTR7 P34969 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067080 0.81 TDP2 (0.40) POLBMEN1KMT2AESR1ESR2
SCHEMBL24720517 0.81 TLR8 (0.45) MCL1CNR1CNR2CA1CA2
SCHEMBL11203627 0.80 PTGS2 (0.41) MCL1POLBCNR1CNR2MAPT
SCHEMBL339799 0.79 TDP2 (0.44) POLBMEN1KMT2ACTDSP1CA1
SCHEMBL16852435 0.78 MCL1 (0.49) MCL1CNR1CNR2CA1CA2
SCHEMBL6423564 0.77 ESR2 (0.53) POLBMAPTESR2TDP2NSD2
SCHEMBL7648903 0.75 PTGS2 (0.38) MCL1CNR1CNR2MAPTTDP2
SCHEMBL12660789 0.75 ESR2 (0.69) MCL1MAPTESR1ESR2
SCHEMBL28019150 0.73 FYN (0.44) POLBMEN1KMT2AMAPTTDP2
SCHEMBL29819560 0.72 MCL1 (0.56) MCL1CNR1CNR2MAPTESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007177180-A EPOXY RESIN VARNISH, PHOTOSENSITIVE RESIN COMPOSITION AND ITS CURED PRODUCT NIPPON KAYAKU CO LTD 2007-07-12 JP disclosed