Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.62 |
| ▸ | CTSK | P43235 | 4/20 | 0.62 |
| ▸ | CTSL | P07711 | 3/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CXCR3 | P49682 | 6/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 3/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5591334 | 0.97 | CTSS (0.62) | CTSSCTSKCTSLCTSBCXCR3 | |
| SCHEMBL5591180 | 0.95 | CTSS (0.68) | CTSSCTSKCTSLCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5591441 | 0.95 | CTSS (0.69) | CTSSCTSKCTSLCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5591828 | 0.93 | CTSS (0.63) | CTSSCTSKCTSLCTSBSLC2A1 | |
| SCHEMBL5590944 | 0.93 | CTSS (0.68) | CTSSCTSKCTSLCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5591489 | 0.91 | CTSS (0.61) | CTSSCTSKCTSLCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5591481 | 0.90 | CTSS (0.60) | CTSSCTSKCTSLCTSBSLC2A1 | |
| SCHEMBL5591423 | 0.90 | CTSS (0.76) | CTSSCTSKCTSLCTSBHDAC6 | |
| Trifluoroacetic Acid SCHEMBL5591343 | 0.88 | CTSL (0.57) | CTSSCTSKCTSLCTSB | |
| SCHEMBL5591471 | 0.88 | CTSS (0.69) | CTSSCTSKCTSLCTSBHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025774-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |