Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL5591441

CN1CCN(Cc2ccc(C(=O)NN(CC3CCCC3)c3nc(C#N)ncc3Br)cc2)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CTSS P25774 5/20 0.69
CTSK P43235 5/20 0.69
CTSL P07711 5/20 0.69
CTSB P07858 1/20 0.69
HDAC6 Q9UBN7 1/20 0.40
SLC2A1 P11166 5/20 0.39
TBK1 Q9UHD2 5/20 0.38
IKBKE Q14164 4/20 0.37
ABL1 P00519 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL5591828 0.96 CTSS (0.63) CTSSCTSKCTSLCTSBHDAC6
SCHEMBL5591423 0.95 CTSS (0.76) CTSSCTSKCTSLCTSBHDAC6
Trifluoroacetic Acid SCHEMBL5591206 0.95 CTSS (0.62) CTSSCTSKCTSLCTSBHDAC6
Trifluoroacetic Acid SCHEMBL5591334 0.95 CTSS (0.62) CTSSCTSKCTSLCTSBHDAC6
Trifluoroacetic Acid SCHEMBL5591489 0.94 CTSS (0.61) CTSSCTSKCTSLCTSBHDAC6
Trifluoroacetic Acid SCHEMBL5591481 0.94 CTSS (0.60) CTSSCTSKCTSLCTSBSLC2A1
Trifluoroacetic Acid SCHEMBL5591343 0.92 CTSL (0.57) CTSSCTSKCTSLCTSB
Trifluoroacetic Acid SCHEMBL5591207 0.91 CTSL (0.57) CTSSCTSKCTSLCTSB
Trifluoroacetic Acid SCHEMBL5591438 0.91 CTSL (0.56) CTSSCTSKCTSLCTSB
SCHEMBL5591471 0.91 CTSS (0.69) CTSSCTSKCTSLCTSBHDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007025774-A2 CYSTEINE PROTEASE INHIBITORS GLAXO GROUP LIMITED (GB) 2007-03-08 WO claimed