Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.70 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.52 |
| ▸ | CCR2 | P41597 | 1/20 | 0.51 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.49 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591952 | 1.00 | ALDH1A1 (0.70) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL2930093 | 0.94 | ALDH1A1 (0.62) | ALDH1A1KDM4EHRH3SIGMAR1CCR2 | |
| SCHEMBL2928521 | 0.92 | KDM4E (0.60) | ALDH1A1KDM4EHRH3CCR2MCHR1 | |
| SCHEMBL5591867 | 0.86 | KDM4E (0.53) | ALDH1A1KDM4EHRH3SIGMAR1SMN1; SMN2 | |
| SCHEMBL5591908 | 0.85 | LMNA (0.53) | ALDH1A1KDM4ECYP2D6CHRM1SMN1; SMN2 | |
| SCHEMBL7937990 | 0.85 | ALDH1A1 (0.95) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL5591700 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EHRH3SIGMAR1CCR2 | |
| SCHEMBL14423362 | 0.83 | KDM4E (0.53) | ALDH1A1KDM4EHRH3SIGMAR1CCR2 | |
| SCHEMBL11227514 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 | |
| SCHEMBL1276590 | 0.83 | ALDH1A1 (1.00) | ALDH1A1KDM4EHRH3SIGMAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |