Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591913 | 0.90 | LMNA (0.56) | LMNAMAPK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL5591952 | 0.85 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1KDM4ECYP2D6CHRM1 | |
| SCHEMBL5591833 | 0.85 | ALDH1A1 (0.70) | SMN1; SMN2ALDH1A1KDM4ECYP2D6CHRM1 | |
| SCHEMBL2930093 | 0.80 | ALDH1A1 (0.62) | LMNAALDH1A1KDM4EADRA2ACHRM1 | |
| SCHEMBL2928521 | 0.79 | KDM4E (0.60) | MAPTHTTNPSR1ALDH1A1KDM4E | |
| SCHEMBL5591843 | 0.78 | CYP19A1 (0.49) | LMNAMAPK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL8170046 | 0.78 | KDM4E (0.62) | MAPK1ALDH1A1KDM4ECYP3A4CYP1A2 | |
| SCHEMBL6482711 | 0.76 | MEN1 (0.61) | MAPK1ALDH1A1KDM4ECYP3A4HPGD | |
| SCHEMBL5591867 | 0.76 | KDM4E (0.53) | MAPTSMN1; SMN2ALDH1A1KDM4EDRD3 | |
| SCHEMBL5591840 | 0.75 | SIGMAR1 (0.54) | LMNAMAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |