Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591952 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1HRH3SIGMAR1L3MBTL3 | |
| SCHEMBL5591833 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1HRH3SIGMAR1L3MBTL3 | |
| SCHEMBL5591878 | 0.83 | SIGMAR1 (0.55) | ALDH1A1MAPTHRH3AKR1C3DRD4 | |
| SCHEMBL5077433 | 0.82 | HRH3 (0.72) | KDM4EALDH1A1HRH3TMEM97SIGMAR1 | |
| SCHEMBL5591932 | 0.82 | MAPT (0.56) | MAPTHRH3AKR1C3DRD4NPC1 | |
| SCHEMBL2930093 | 0.81 | ALDH1A1 (0.62) | KDM4EALDH1A1HRH3DRD4SIGMAR1 | |
| SCHEMBL2928521 | 0.80 | KDM4E (0.60) | KDM4EALDH1A1MAPTHRH3 | |
| SCHEMBL5591821 | 0.79 | CYP19A1 (0.51) | KDM4EALDH1A1MAPTHRH3DRD4 | |
| SCHEMBL5591894 | 0.79 | SMN1; SMN2 (0.70) | KDM4EALDH1A1MAPTAKR1C3DRD4 | |
| SCHEMBL5591913 | 0.77 | LMNA (0.56) | ALDH1A1MAPTAKR1C3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |