Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PRNP | P04156 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9228099 | 0.91 | MAPT (0.52) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| SCHEMBL5591919 | 0.86 | NR4A2 (0.49) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| SCHEMBL5762904 | 0.83 | CYP1A2 (0.58) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| Hydrochloric Acid SCHEMBL9229003 | 0.81 | CYP1A2 (0.56) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| SCHEMBL9033128 | 0.81 | NPC1 (0.50) | KMT2AMEN1L3MBTL1ALDH1A1HTT | |
| SCHEMBL17151063 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP2D6SRCTGFBR1SMN1; SMN2 | |
| SCHEMBL9228994 | 0.80 | NR4A2 (0.54) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| SCHEMBL13210167 | 0.78 | LMNA (0.54) | KDM4EPRNPRXFP1NR4A2SOS2 | |
| SCHEMBL2825389 | 0.78 | ALDH1A1 (0.60) | CYP1A2CYP2D6SMN1; SMN2KMT2AMAPT | |
| SCHEMBL28409135 | 0.76 | L3MBTL1 (0.49) | KDM4ESRCTGFBR1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007104696-A1 | ANTIMALARIAL AGENTS HAVING POLYAROMATIC STRUCTURE | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2007-09-20 | — | — | WO | disclosed |
| EP-0669320-A2 | Benzoylquinoiline derivatives | NIHON BAYER AGROCHEM K.K. (JP) | 1995-08-30 | — | — | EP | disclosed |