Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 10/20 | 0.76 |
| ▸ | HTR7 | P34969 | 10/20 | 0.76 |
| ▸ | MEN1 | O00255 | 2/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.76 |
| ▸ | DRD2 | P14416 | 5/20 | 0.69 |
| ▸ | HTR2A | P28223 | 3/20 | 0.69 |
| ▸ | HTR6 | P50406 | 3/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.61 |
| ▸ | DRD3 | P35462 | 2/20 | 0.58 |
| ▸ | DRD4 | P21917 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5592259 | 0.99 | HTR1A (0.74) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| SCHEMBL5592274 | 0.95 | HTR1A (0.69) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5592366 | 0.94 | HTR1A (0.68) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| SCHEMBL5592187 | 0.91 | HTR7 (0.73) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL8156434 | 0.90 | HTR1A (0.65) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5592294 | 0.90 | HTR7 (0.71) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| SCHEMBL5592295 | 0.88 | HTR7 (0.97) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| Hydrochloric Acid SCHEMBL5592269 | 0.87 | HTR7 (0.95) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| SCHEMBL6017582 | 0.86 | HTR7 (1.00) | HTR1AHTR7MEN1KMT2ACYP1A2 | |
| SCHEMBL5592137 | 0.86 | HTR1A (0.57) | HTR1AHTR7MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |