Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.57 |
| ▸ | HTR7 | P34969 | 8/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 3/20 | 0.53 |
| ▸ | HTR2A | P28223 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5592258 | 0.89 | HTR7 (0.73) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5592140 | 0.88 | HTR7 (0.71) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL5592209 | 0.88 | HTR1A (0.51) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5592289 | 0.87 | ADRA1B (0.50) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL6072530 | 0.87 | HTR1A (0.49) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL5592252 | 0.86 | HTR1A (0.76) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL5592292 | 0.86 | HTR1A (0.56) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5592259 | 0.85 | HTR1A (0.74) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL5592204 | 0.85 | HTR1A (0.55) | HTR1AHTR7MEN1CYP1A2CYP2C9 | |
| SCHEMBL4516386 | 0.84 | ADRA1B (0.50) | HTR1AHTR7MEN1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | claimed |
| WO-2007029078-A2 | SUCCINIMIDE AND GLUTARIMIDE DERIVATIVES AS ADRENERGIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |