Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | GPR6 | P46095 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593179 | 0.95 | CTSL (0.51) | CTSLCTSSCTSKCTSBACKR3 | |
| Trifluoroacetic Acid SCHEMBL5592876 | 0.89 | CTSL (0.55) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5593235 | 0.89 | CTSL (0.55) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5592919 | 0.87 | CTSL (0.52) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5593218 | 0.87 | CTSL (0.56) | CTSLCTSSCTSKCTSBSLC2A1 | |
| SCHEMBL8242605 | 0.87 | CTSS (0.60) | CTSLCTSSCTSKCTSBCHEK1 | |
| Trifluoroacetic Acid SCHEMBL5592941 | 0.86 | CTSL (0.51) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5592808 | 0.85 | CTSL (0.56) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5592935 | 0.85 | CTSL (0.55) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL5592668 | 0.85 | CTSL (0.58) | CTSLCTSSCTSKCTSBSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |