Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.55 |
| ▸ | CTSK | P43235 | 1/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 9/20 | 0.39 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5592941 | 0.95 | CTSL (0.51) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL8236817 | 0.92 | CTSL (0.65) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5592721 | 0.90 | CTSL (0.56) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5592895 | 0.90 | CTSL (0.60) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5593161 | 0.89 | CTSL (0.60) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5592907 | 0.88 | CTSL (0.61) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5593202 | 0.88 | CTSL (0.54) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL8244881 | 0.88 | CTSL (0.58) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL8236804 | 0.87 | CTSS (0.61) | CTSLCTSBCTSSCTSKACKR3 | |
| SCHEMBL5592917 | 0.87 | CTSL (0.58) | CTSLCTSBCTSSCTSKACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |