Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | CTSK | P43235 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 1/20 | 0.54 |
| ▸ | CXCR3 | P49682 | 8/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 4/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8236804 | 0.94 | CTSS (0.61) | CTSLCTSSCTSKCTSBCXCR3 | |
| SCHEMBL5593161 | 0.93 | CTSL (0.60) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL8238304 | 0.92 | CTSK (0.64) | CTSLCTSSCTSKCTSBCXCR3 | |
| SCHEMBL5592895 | 0.92 | CTSL (0.60) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL5592654 | 0.90 | CTSL (0.61) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL5592721 | 0.89 | CTSL (0.56) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL5592666 | 0.89 | CTSL (0.61) | CTSLCTSSCTSKCTSBACKR3 | |
| Trifluoroacetic Acid SCHEMBL5593236 | 0.89 | CTSL (0.49) | CTSLCTSSCTSKCTSBCXCR3 | |
| SCHEMBL5592751 | 0.89 | CTSL (0.59) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL5592862 | 0.88 | CTSL (0.55) | CTSLCTSSCTSKCTSBACKR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | disclosed |