Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | GPR6 | P46095 | 5/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 2/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.34 |
| ▸ | DDR1 | Q08345 | 3/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.32 |
| ▸ | CCR3 | P51677 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5591897 | 0.96 | CTSL (0.46) | CTSLCTSSCTSKCTSBJAK2 | |
| SCHEMBL8245495 | 0.90 | CTSL (0.47) | CTSLCTSSCTSKCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5591672 | 0.88 | CTSS (0.56) | CTSLCTSSCTSKCTSBGPR6 | |
| SCHEMBL5591269 | 0.86 | CTSL (0.57) | CTSLCTSSCTSKCTSBJAK2 | |
| SCHEMBL5591381 | 0.84 | CTSL (0.60) | CTSLCTSSCTSKCTSBGPR6 | |
| Trifluoroacetic Acid SCHEMBL5591334 | 0.83 | CTSS (0.62) | CTSLCTSSCTSKCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5592940 | 0.83 | CTSL (0.48) | CTSLCTSSCTSKCTSBGPR6 | |
| Trifluoroacetic Acid SCHEMBL5591206 | 0.82 | CTSS (0.62) | CTSLCTSSCTSKCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL3166832 | 0.81 | CTSL (0.49) | CTSLCTSSCTSKCTSBCXCR3 | |
| Trifluoroacetic Acid SCHEMBL5591343 | 0.81 | CTSL (0.57) | CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025774-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |