Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.68 |
| ▸ | CTSS | P25774 | 2/20 | 0.68 |
| ▸ | CTSK | P43235 | 2/20 | 0.68 |
| ▸ | CTSB | P07858 | 1/20 | 0.68 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.41 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593158 | 0.95 | CTSL (0.74) | CTSLCTSSCTSKCTSBACKR3 | |
| Trifluoroacetic Acid SCHEMBL5592914 | 0.91 | CTSL (0.69) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3159904 | 0.87 | CTSS (0.49) | CTSLCTSSCTSKCTSBSLC2A1 | |
| Trifluoroacetic Acid SCHEMBL3319243 | 0.87 | CTSS (0.90) | CTSLCTSSCTSKCTSBSLC2A1 | |
| SCHEMBL8242630 | 0.86 | CTSL (0.76) | CTSLCTSSCTSKCTSBKISS1R | |
| Trifluoroacetic Acid SCHEMBL5592904 | 0.86 | CTSL (0.66) | CTSLCTSSCTSKCTSBSLC2A1 | |
| SCHEMBL3169523 | 0.82 | CTSS (0.53) | CTSLCTSSCTSKCTSBACKR3 | |
| SCHEMBL5592896 | 0.81 | CTSS (1.00) | CTSLCTSSCTSKCTSB | |
| Trifluoroacetic Acid SCHEMBL5592848 | 0.81 | CTSL (0.79) | CTSLCTSSCTSKCTSBSLC2A1 | |
| SCHEMBL5592724 | 0.81 | CTSL (0.54) | CTSLCTSSCTSKCTSBKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007025775-A2 | CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-03-08 | — | — | WO | claimed |